The Rabbit Hole of Research
Rabbit Hole of Research
The Mini: Future of Medicine
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The Mini: Future of Medicine

The RHR crew talks about health-span over lifespan, then dives into seed preservation, apple varieties, cloning clarifications, and pig liver xenotransplantation breakthroughs.

In this episode of The Mini, Joe, Georgia, and a virtual Nick (recovering from norovirus) revisit their conversation, Episode 56: Medicine of the Future with fantasy author and physician Davis Ashura, emphasizing his key message: your best health starts in your kitchen, not your doctor’s office, and focusing on health span (quality of years) over lifespan (quantity of years).

This forked into a conversation about vegetable/fruit biodiversity and seed preservation. The crew discusses a Midwest native seed-saving coalition involving 300 ecologists across 150 institutions in 11 states, the practicalities of saving heirloom seeds (cross-pollination risks), why Red Delicious apples aren’t so delicious anymore, why, contrary to logic, eating more vegetables could save our favorite varieties, and the Norway seed vault. They also address the reality of food deserts and unequal access to fresh produce.

Science updates include clarifications from last episode about Dolly the sheep’s cloning (her “sister” clones lived normal lifespans), discussion about gene editing and Colossal Laboratories’ “dire wolf” de-extinction project, and a breakthrough from China where surgeons used a genetically modified pig liver to keep a patient alive while waiting for a human transplant organ. FDA trials now approved in the US.

Plus: upcoming episode teasers (chatbots and data centers/climate change), norovirus on cruise ship, and what the crew is reading and watching: Virginia Tufte, Stephen Graham Jones, Alice Feeney, The Marvelous Mrs. Maisel, Shrinking, and The Traitors UK.


Where to Find Davis Ashura:

  • Website: davisashura.com

  • The Anchored Worlds Universe

  • Audiobooks narrated by: Nick Podehl and Travis Baldree


Listen to Episode 56:

Rabbit Hole of Research

Medicine of the Future: From Fantasy to Patient Care

Medicine of the Future: From Fantasy to Patient Care

In the 56th episode of Rabbit Hole of Research, Joe, Nick, and Georgia are joined by Davis Ashura, endocrinologist, epic fantasy author, and creator of the Anchored Worlds universe, to explore where magical healing meets medical reality. Davis brings a unique dual perspective: treating chronic diseases like diabetes and hypertension by day, and writing …


Check out what the RHR crew is creating:

Joe:


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Future Events to Hang with the Crew:

Podcast Cross-Appearances

Events & Conventions:


Upcoming Episodes

*The Mini will now be every other episode!

  • Episode 58 – The Science of Chatbots & Human Connection

    Guests: Lily & Generoso

    Diving into AI communication, computational science, and how chatbots are reshaping human interaction with MIT scientist-turned-writer Lily and illustrator/filmmaker Generoso.

  • Episode 60 – Lassoing the Truth Serum
    Guest: David Detmer
    Exploring the philosophy and science of truth, deception, and the Handwavium of Wonder Woman’s lasso.

  • Episode 62 – The Science of Fear: Phobias, Physiology & Splatterpunk
    Guest: Phrique
    Diving into the biology of fear, phobia formation, and the extreme horror genre of splatterpunk with author Phrique.

  • Episode 64 – Planetary Defense: Saving Earth from Other Worldly Impact
    Guest: Charles Blue
    Exploring asteroid detection, planetary defense systems, and what it takes to protect Earth from cosmic collisions.


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What the Crew is Digging, Links, Resources, and Topics Mentioned in mini and/or full episode:

Science Updates & Research:

Seed Preservation:

Cloning & Genetics:

  • Dolly the Sheep – Clarification: While Dolly died at age 6 with short telomeres, her “sister” clones from the same adult cell line lived to normal ages without premature aging

  • Colossal Biosciences – De-extinction projects including dire wolf, woolly mammoth, dodo bird

    • Dire Wolf De-Extinction – Using gray wolf DNA with genetic modifications to recreate extinct apex predator (extinct ~10,000 years)

  • Xenotransplantation Breakthrough:

  • Genetics & Cloning Concepts:

    • Telomeres – DNA protective caps that shorten with age, and linked to aging

    • Pluripotent stem cells – Master cells that can become any cell type

    • Differentiated adult cells – Cells that have already specialized

    • BRCA genes – Breast cancer susceptibility genes

    • CRISPR – Gene editing tool: (short for “clustered regularly interspaced short palindromic repeats”) is a technology that research scientists use to selectively modify the DNA of living organisms.

    • Epigenetics – how environment, behavior, and lifestyle (e.g., diet, stress, toxins) alter gene expression—turning genes "on" or "off"—without changing the underlying DNA sequence.


    Books Mentioned:

    Joe Reading:

    • Artful Sentences: Syntax as Style by Virginia Tufte

    • Dear Writer by Maggie Smith

    • The Change Agent by Daniel Suarez

    Nick Reading:

    • My Heart Is a Chainsaw by Stephen Graham Jones (Indian Lake Trilogy #1)

    • Don’t Fear the Reaper by Stephen Graham Jones (Indian Lake Trilogy #2)

    • The Killer on the Road by Stephen Graham Jones

    Georgia Reading:

    • My Husband’s Wife by Alice Feeney – Thriller/bestseller

    • How High We Go in the Dark – Novel with interlocking short stories (mentioned pig research story)

    Also Mentioned:

    • Only Good Indians by Stephen Graham Jones

    • The Buffalo Hunter Hunter by Stephen Graham Jones


    TV Shows & Media:

    • Shrinking (Apple TV+) – Joe watching

    • The Traitors UK – Joe watching (psychological game show, werewolf-style)

    • The Marvelous Mrs. Maisel (Amazon Prime) – Nick watching, almost done with final season


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